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Chief Executive Officer
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Chief Technology Officer
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Chief Scientific Officer
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Director of Technology Development
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co-founded Virtual Chemistry, Inc. (VCI) with Jon Hurley
and Tom Thacher in November 1995. Terry holds degrees in computer science
and chemistry from the University of Illinois, and a Ph.D. in quantum computational
chemistry from Caltech.
At Deltagen, Dr. Coley served as the Vice President of Information Technology.
There he created standards for IT infrastructure, software development, and IT hiring practices.
Key accomplishments include the design and development of DeltaDiscovery, a metadata-driven system
for acquisition, warehousing, and web-display of laboratory data. This software hosted and
delivered all revenue-generating data for Deltagen's DeltaBase product, a subscription
database of functional genomics information.
Before establishing VCI, Dr. Coley founded a company in 1989 to sell a
load balancing system which he designed for parallel computers. In 1993,
Dr. Coley became a full-time consultant to Vestar, Inc. studying
molecular modeling approaches in their liposomal drug delivery group.
He joined Biosym Technologies in 1994 and became a Project Leader in the
life sciences business unit where he implemented the inter-process
communication facilities and designed the initial Message Passing
Interface-based parallelism in the Discover molecular dynamics program.
Dr. Coley has extensive experience in parallel computing, 3D computer
graphics, and software development tools and technologies. Dr. Coley is
directly involved with many projects at VCI. His current interests
include the design and implementation of chemical informatics solutions
for the pharmaceutical and chemical industries.
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received a B.A. in Chemistry from Cambridge University in 1986, and an
M.S. in theoretical chemistry from Caltech in 1988.
At Deltagen, Mr. Hurley served as the Director of Software Architecture. He
was responsible for many of the key productivity designs, including a
metadata-driven web development environment that allowed deployment of
new web code (reporting, data entry, and navigation) with no new coding.
Between 1988 and 1995 he held scientific development and management
positions at Molecular Simulations, Inc. and Biosym Technologies, Inc.
At Biosym, Mr. Hurley managed the development of the Discover program,
the pre-eminent molecular mechanics code in the industry. Some of the
projects that Mr. Hurley has been involved with at since joining VCI
include VAnimator, a Visual C++ molecular graphics program that VCI
uses to produce sophisticated chemical animations for the marketing
and legal communities; an Automated Revenue Collection system for a
transit agency which features a high performing transaction processing
component architected on Sybase SQL Server; and a client/ server program
using Visual Basic and Oracle to enable construction and maintenance of
combinatorial chemistry libraries.
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received his Ph.D. at Boston College in the area of statistical mechanics.
He then took a post-doctoral position at Princeton University to study the dynamics
of biomolecules.
At Deltagen, Dr. Thacher developed key components of the
DeltaDiscovery framework, including a metadata-driven graphing engine
for the web. He also created software to manage large amounts of
Affymetrix array data in a relational database. The system allowed
for key up/down-regulated genes associated with mouse knockouts to be
identified and reported efficiently.
Prior to VCI, Dr. Thacher was Senior Scientist at Biosym Technologies, Inc.
where he worked in the Potential Energy Function Consortium and then as a
scientific manager in the Discover development group. Additionally, he
worked on a number of contract research grants in the area of molecular
modeling for industrial customers. Dr. Thacher was also awarded a Phase I
and Phase II NIH research grant to apply sensitivity analysis to bimolecular
modeling. Dr. Thacher is directly involved with many projects at Virtual
Chemistry Inc., including the design and development of an extensive
Java-based interface to a client's in-house combinatorial chemistry software.
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joined Virtual Chemistry in August, 2003, bringing broad experience in
life sciences, software development, and engineering. Dr. Thelen joined
Virtual Chemistry from Deltagen, Inc. where he served as Group Leader
of Application Development. While at Deltagen, Dr. Thelen played a key
role in LIMS (laboratory information management systems) development,
data warehousing and data management implementations, and development of
Deltagen's functional genomics platform DeltaBase.
Dr. Thelen has consulted for such companies as: Gensym, TRW, BMC
Software, Atlantic Research Corporation, US Army LIA Labs, Computer
Sciences Corporation, US Air Force, and Ribozyme Pharmaceuticals.
Consulting engagements include such diverse applications as: Real-time
fault diagnosis (root-cause analysis) of distributed software and
network systems; dynamic scheduling, planning, and optimization
applications; business process modeling and re-engineering; laboratory
automation and integration applications; and knowledge management system
development.
Dr. Thelen did post-doctoral work with Dr. Robert L. Welch of Gensym
Corporation working on applications of Bayesian network technology to
fault diagnosis and real-time reliability analysis after receiving Ph.D.
and M.S. degrees in Chemical Engineering from the University of
Colorado, Boulder. Dr. Thelen also holds a B.S. in Chemical Engineering
from Michigan Technological University.
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